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Adults with moderate or severe symptoms also were more likely than those with no or minimal symptoms of anxiety in the past 2 weeks to have been past year or past month users of most of the other substances shown in Table A.46B

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ZYN eliminates combustion, meaning users avoid: Tar Carbon monoxide Smoke-related toxins However, nicotine itself still has effects: Raises heart rate and blood pressure Can reinforce addiction May affect developing brains (especially under age 25) Can irritate gums and oral tissue Smoother or smoke-free does not mean risk-free

Research to develop a vaccine is ongoing